DatasetLactate high vs low_Ranked
PhenotypeNoPhenotypeAvailable
Upregulated in classna_pos
GeneSetHALLMARK_KRAS_SIGNALING_UP
Enrichment Score (ES)0.27275234
Normalized Enrichment Score (NES)1.7525212
Nominal p-value0.0048076925
FDR q-value0.03668281
FWER p-Value0.125
Table: GSEA Results Summary



Fig 1: Enrichment plot: HALLMARK_KRAS_SIGNALING_UP   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

SYMBOLRANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1Gpnmb32.2130.0237Yes
2C3ar142.2070.0483Yes
3Ctss142.0880.0685Yes
4Mafb221.9430.0878Yes
5Cd37491.7630.0987Yes
6Lat2641.6850.1128Yes
7Fcer1g951.5970.1204Yes
8Itgb21381.4980.1230Yes
9Etv51421.4820.1385Yes
10Csf2ra1431.4780.1549Yes
11Tnfrsf1b1711.4120.1616Yes
12Adam82221.3510.1598Yes
13Dock22291.3330.1726Yes
14Spp12321.3270.1867Yes
15Tmem1002581.2770.1925Yes
16Ikzf12851.2360.1975Yes
17Mmp113131.2090.2019Yes
18Ace3291.1850.2100Yes
19Mmd3491.1660.2166Yes
20Nrp13531.1580.2285Yes
21Nin3591.1530.2397Yes
22Il2rg3801.1280.2455Yes
23Lcp14161.0840.2458Yes
24Tspan74871.0040.2333Yes
25Mmp94990.9930.2407Yes
26Plvap5120.9770.2475Yes
27Adgra25580.9420.2429Yes
28Sparcl15660.9380.2510Yes
29Pecam16580.8450.2296Yes
30Laptm56590.8440.2391Yes
31Gng116620.8400.2478Yes
32Irf86630.8400.2571Yes
33Ets16710.8310.2640Yes
34Adgrl46920.8170.2664Yes
35Akap127130.8010.2686Yes
36Eng7330.7760.2708Yes
37Gucy1a17590.7520.2707Yes
38Prrx17780.7270.2728Yes
39Psmb88380.6780.2604No
40Cxcr48470.6730.2652No
41G0s28780.6450.2622No
42Traf19070.6260.2598No
43Gprc5b9270.6120.2602No
44Cfh10300.5480.2318No
45Plau10590.5340.2283No
46Plaur10980.5040.2211No
47Mtmr101182-0.5150.1988No
48Btbd31191-0.5170.2019No
49Rabgap1l1215-0.5250.2000No
50Dnmbp1239-0.5300.1981No
51Ano11324-0.5470.1758No
52Ptcd21568-0.6070.1005No
53Yrdc1600-0.6160.0969No
54Prdm11634-0.6280.0928No
55Rbm41734-0.6660.0668No
56Hbegf1860-0.7090.0325No
57Ank1878-0.7130.0347No
58Slpi2011-0.766-0.0013No
59Plat2156-0.832-0.0407No
60Sox92201-0.860-0.0460No
61Cbr42234-0.884-0.0469No
62Ccnd22242-0.887-0.0394No
63Crot2333-0.945-0.0593No
64Jup2337-0.950-0.0497No
65Btc2354-0.969-0.0443No
66Tspan12419-1.017-0.0545No
67Glrx2526-1.119-0.0779No
68Plek22648-1.279-0.1045No
69Trib22678-1.331-0.0994No
70Mpzl22710-1.388-0.0944No
71Cab39l2750-1.490-0.0910No
72Igfbp32753-1.492-0.0750No
73Cfb2772-1.529-0.0640No
74Galnt32845-1.733-0.0690No
75Aldh1a32868-1.845-0.0559No
76Adamdec12890-1.956-0.0412No
77Pigr2910-2.092-0.0242No
78Tmem1582930-2.218-0.0059No
79Cpe3023-3.8020.0054No
Table: GSEA details [plain text format]



Fig 2: HALLMARK_KRAS_SIGNALING_UP: Random ES distribution   
Gene set null distribution of ES for HALLMARK_KRAS_SIGNALING_UP